The SARS-Cov virus, which studies the highest gene sequence similarity, modeled the covid-19 virus. Combined with high-precision molecular dynamics calculation and drug molecular simulation research and development platform, the three-dimensional structure of 3CLpro and PLpro potential targets on covid-19 viruses and the Siper protein associated with infection was obtained. New screening of older
Laying the foundation for the development of coping drugs of COVID-19.